The Enough Abuse Campaign was developed in Massachusetts by a collaborative whose efforts have been described by the U.S. Centers for Disease Control and Prevention (CDC) as ‘trailblazing’. In 2003, Missouri leaders came together to form the Missouri Child Sexual Abuse Prevention Partnership and voted to join Massachusetts in developing the Campaign. New approaches to prevention are being evaluated in these Missouri communities – St. Joseph, Phelps County, Ripley County, Independence and Barceda Families. In collaboration with the Partnership, a broad range of local organizations in these communities are leading the way in efforts to prevent child sexual abuse. These organizations and those who lead them represent the best of what our state has to offer – deep dedication to children and their well being, and courage to find effective strategies to solve a complex and challenging problem. The Partnership is convinced that lessons learned during this pilot effort will improve the protection of children not only in these locations but also in communities all across our state and nation.